{"id":3055,"date":"2026-05-10T12:55:21","date_gmt":"2026-05-10T10:55:21","guid":{"rendered":"https:\/\/momenti.info\/index.php\/2026\/05\/10\/nje-vitamine-mund-te-ndihmoje-ne-trajtimin-e-melcise-se-dhjamosur-shkencetaret-zbulojne-celesin-molekular\/"},"modified":"2026-05-10T12:55:21","modified_gmt":"2026-05-10T10:55:21","slug":"nje-vitamine-mund-te-ndihmoje-ne-trajtimin-e-melcise-se-dhjamosur-shkencetaret-zbulojne-celesin-molekular","status":"publish","type":"post","link":"https:\/\/momenti.info\/index.php\/2026\/05\/10\/nje-vitamine-mund-te-ndihmoje-ne-trajtimin-e-melcise-se-dhjamosur-shkencetaret-zbulojne-celesin-molekular\/","title":{"rendered":"Nj\u00eb vitamin\u00eb mund t\u00eb ndihmoj\u00eb n\u00eb trajtimin e m\u00ebl\u00e7is\u00eb s\u00eb dhjamosur, shkenc\u00ebtar\u00ebt zbulojn\u00eb \u201c\u00e7el\u00ebsin\u201d molekular"},"content":{"rendered":"<div>\n<p><strong>Studimi i ri tregon se molekula miR-93 mund t\u00eb luaj\u00eb rol t\u00eb r\u00ebnd\u00ebsish\u00ebm n\u00eb grumbullimin e yndyr\u00ebs n\u00eb m\u00ebl\u00e7i, nd\u00ebrsa nj\u00eb p\u00ebrb\u00ebr\u00ebs i njohur po shqyrtohet si mund\u00ebsi e ardhshme terapeutike<\/strong><\/p>\n<p>S\u00ebmundja metabolike e m\u00ebl\u00e7is\u00eb s\u00eb dhjamosur, e njohur si MASLD, lidhet me mbipesh\u00ebn, rezistenc\u00ebn ndaj insulin\u00ebs dhe diabetin e tipit 2. Sipas <strong>Ulsan National Institute of Science and Technology<\/strong>, rreth 25 deri n\u00eb 30 p\u00ebr qind e popullsis\u00eb globale mund t\u00eb jet\u00eb e prekur nga kjo gjendje, e cila shpesh p\u00ebrparon pa simptoma t\u00eb dukshme. <\/p>\n<hr\/>\n<p>MASLD ndodh kur yndyra grumbullohet n\u00eb m\u00ebl\u00e7i n\u00eb prani t\u00eb \u00e7rregullimeve metabolike, si mbipesha, trigliceridet e larta, diabeti i tipit 2 ose presioni i lart\u00eb i gjakut. N\u00eb fazat e para, shum\u00eb persona nuk ndiejn\u00eb asgj\u00eb, por me kalimin e koh\u00ebs gjendja mund t\u00eb \u00e7oj\u00eb n\u00eb inflamacion, fibroz\u00eb, cirroz\u00eb dhe d\u00ebmtim serioz t\u00eb m\u00ebl\u00e7is\u00eb. N\u00eb studimin e botuar n\u00eb revist\u00ebn shkencore <strong>Metabolism<\/strong>, autor\u00ebt theksojn\u00eb se MASLD p\u00ebrfshin nj\u00eb spekt\u00ebr gjendjesh, nga dhjamosja e thjesht\u00eb deri te format m\u00eb t\u00eb avancuara si MASH, fibroza dhe cirroza. <\/p>\n<p>Ekipi i udh\u00ebhequr nga Jang Hyun Choi, nga Ulsan National Institute of Science and Technology, n\u00eb bashk\u00ebpunim me studiues nga Pusan National University dhe Ulsan University Hospital, ka identifikuar miR-93 si faktor t\u00eb r\u00ebnd\u00ebsish\u00ebm n\u00eb p\u00ebrparimin e MASLD. Sipas UNIST, kjo molekul\u00eb u gjet n\u00eb nivele t\u00eb larta n\u00eb indin e m\u00ebl\u00e7is\u00eb te pacient\u00ebt me MASLD dhe te minjt\u00eb e ushqyer me diet\u00eb t\u00eb pasur me yndyr\u00eb dhe fruktoz\u00eb, transmeton Telegrafi.<\/p>\n<p>MicroRNA-t\u00eb jan\u00eb molekula t\u00eb vogla q\u00eb ndikojn\u00eb n\u00eb aktivitetin e gjeneve. N\u00eb k\u00ebt\u00eb rast, miR-93 duket se pengon veprimin e SIRT1, nj\u00eb gjen i r\u00ebnd\u00ebsish\u00ebm p\u00ebr p\u00ebrdorimin e energjis\u00eb dhe metabolizmin e yndyrave. T\u00eb dh\u00ebnat e publikuara n\u00eb <strong>Metabolism <\/strong>tregojn\u00eb se miR-93 e shtyp SIRT1 dhe dob\u00ebson rrug\u00ebn sinjalizuese LKB1 AMPK, e cila ndihmon qelizat t\u00eb ruajn\u00eb ekuilibrin energjetik. <\/p>\n<p>Kur SIRT1 frenohet, m\u00ebl\u00e7ia priret t\u00eb ruaj\u00eb m\u00eb shum\u00eb yndyr\u00eb, n\u00eb vend q\u00eb ta djeg\u00eb at\u00eb. Studiuesit vun\u00eb re se miR-93 ul oksidimin e acideve yndyrore dhe rrit proceset q\u00eb lidhen me prodhimin e kolesterolit.<\/p>\n<p>P\u00ebr t\u00eb par\u00eb n\u00ebse bllokimi i miR-93 mund ta p\u00ebrmir\u00ebsonte gjendjen, studiuesit krijuan minj q\u00eb nuk mund t\u00eb prodhonin k\u00ebt\u00eb molekul\u00eb. Edhe kur u ushqyen me diet\u00eb t\u00eb pasur me yndyr\u00eb dhe fruktoz\u00eb, ata zhvilluan duksh\u00ebm m\u00eb pak grumbullim yndyre n\u00eb m\u00ebl\u00e7i. N\u00eb revist\u00ebn shkencore <strong>Metabolism<\/strong>, studiuesit raportojn\u00eb se mungesa e miR-93 u lidh me aktivizimin e gjeneve q\u00eb ndihmojn\u00eb djegien e acideve yndyrore dhe me uljen e atyre q\u00eb marrin pjes\u00eb n\u00eb biosintez\u00ebn e kolesterolit. <\/p>\n<p>N\u00eb faz\u00ebn tjet\u00ebr, studiuesit testuan 150 barna t\u00eb miratuara nga FDA p\u00ebr t\u00eb par\u00eb n\u00ebse ndonj\u00ebri prej tyre mund ta ulte nivelin e miR-93. <strong>ScienceDaily <\/strong>raporton se<strong\/>, niacina, e njohur edhe si vitamina B3, doli si p\u00ebrb\u00ebr\u00ebsi m\u00eb efektiv n\u00eb k\u00ebt\u00eb kontroll laboratorik. Te minjt\u00eb e trajtuar, nivelet e miR-93 ran\u00eb, aktiviteti i SIRT1 u rrit dhe u p\u00ebrmir\u00ebsuan rrug\u00ebt e p\u00ebrpunimit t\u00eb yndyr\u00ebs n\u00eb m\u00ebl\u00e7i. <\/p>\n<p class=\"shortcode-media shortcode-media-rebelmouse-image\"> <img decoding=async data-opt-id=1940326996  fetchpriority=\"high\" id=\"f6441\" data-rm-shortcode-id=\"8a9a602d8694f8f81a992cbf8865ab0d\" data-rm-shortcode-name=\"rebelmouse-image\" class=\"rm-shortcode rm-lazyloadable-image \" lazy-loadable=\"true\" src='0 0 688 458'%3E%3C\/svg%3E\" data-runner-src=\"https:\/\/telegrafi.com\/media-library\/image.jpg?id=66715639&amp;width=980\" width=\"688\" height=\"458\" alt=\"\"\/> <\/p>\n<p>Megjithat\u00eb, k\u00ebto rezultate nuk do t\u00eb thon\u00eb se niacina \u00ebsht\u00eb tashm\u00eb trajtim i provuar p\u00ebr m\u00ebl\u00e7in\u00eb e dhjamosur. Autor\u00ebt theksojn\u00eb se nevojiten studime klinike te njer\u00ebzit p\u00ebr t\u00eb v\u00ebrtetuar n\u00ebse efekti i par\u00eb n\u00eb modele laboratorike p\u00ebrkthehet n\u00eb p\u00ebrfitim real p\u00ebr pacient\u00ebt.<\/p>\n<p>Edhe pse b\u00ebhet fjal\u00eb p\u00ebr vitamin\u00eb, n\u00eb doza t\u00eb larta niacina sillet si bar dhe mund t\u00eb shkaktoj\u00eb efekte an\u00ebsore. Prandaj nuk duhet p\u00ebrdorur p\u00ebr vet\u00ebtrajtim, pa k\u00ebshill\u00eb dhe mbik\u00ebqyrje mjek\u00ebsore. Sipas <strong>ClinicalTrials.gov<\/strong>, nj\u00eb studim klinik me kodin NCT06843148, i udh\u00ebhequr nga Universit\u00e9 de Sherbrooke, po vler\u00ebson se si niacina ndikon n\u00eb shp\u00ebrndarjen e yndyr\u00ebs dhe p\u00ebrgjigjet metabolike te personat me MASLD. <\/p>\n<p>Ky zbulim tregon se rruga miR-93\/SIRT1 mund t\u00eb jet\u00eb objektiv i ri p\u00ebr trajtime t\u00eb ardhshme. Deri at\u00ebher\u00eb, baza e kujdesit mbetet ndryshimi i stilit t\u00eb jetes\u00ebs: humbja graduale e pesh\u00ebs, aktiviteti fizik, ulja e sheqernave dhe karbohidrateve t\u00eb rafinuara, kufizimi i alkoolit, si dhe kontrolli i diabetit, triglicerideve dhe presionit t\u00eb gjakut. <strong>\/Telegrafi\/<\/strong><\/p>\n<\/div>\n<p><a href=\"https:\/\/telegrafi.com\/nje-vitamine-mund-te-ndihmoje-ne-trajtimin-e-melcise-se-dhjamosur-shkencetaret-zbulojne-celesin-molekular\/\">source<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Studimi i ri tregon se molekula miR-93 mund t\u00eb luaj\u00eb rol t\u00eb r\u00ebnd\u00ebsish\u00ebm n\u00eb grumbullimin e yndyr\u00ebs n\u00eb m\u00ebl\u00e7i, nd\u00ebrsa nj\u00eb p\u00ebrb\u00ebr\u00ebs i njohur po shqyrtohet si mund\u00ebsi e ardhshme terapeutike S\u00ebmundja metabolike e m\u00ebl\u00e7is\u00eb s\u00eb dhjamosur, e njohur si MASLD, lidhet me mbipesh\u00ebn, rezistenc\u00ebn ndaj insulin\u00ebs dhe diabetin e tipit 2. Sipas Ulsan National [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3057,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"","fifu_image_alt":"","footnotes":""},"categories":[4],"tags":[],"class_list":{"0":"post-3055","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-lajme"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Nj\u00eb vitamin\u00eb mund t\u00eb ndihmoj\u00eb n\u00eb trajtimin e m\u00ebl\u00e7is\u00eb s\u00eb dhjamosur, shkenc\u00ebtar\u00ebt zbulojn\u00eb \u201c\u00e7el\u00ebsin\u201d molekular - Momenti<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/momenti.info\/index.php\/2026\/05\/10\/nje-vitamine-mund-te-ndihmoje-ne-trajtimin-e-melcise-se-dhjamosur-shkencetaret-zbulojne-celesin-molekular\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nj\u00eb vitamin\u00eb mund t\u00eb ndihmoj\u00eb n\u00eb trajtimin e m\u00ebl\u00e7is\u00eb s\u00eb dhjamosur, shkenc\u00ebtar\u00ebt zbulojn\u00eb \u201c\u00e7el\u00ebsin\u201d molekular - Momenti\" \/>\n<meta property=\"og:description\" content=\"Studimi i ri tregon se molekula miR-93 mund t\u00eb luaj\u00eb rol t\u00eb r\u00ebnd\u00ebsish\u00ebm n\u00eb grumbullimin e yndyr\u00ebs n\u00eb m\u00ebl\u00e7i, nd\u00ebrsa nj\u00eb p\u00ebrb\u00ebr\u00ebs i njohur po shqyrtohet si mund\u00ebsi e ardhshme terapeutike S\u00ebmundja metabolike e m\u00ebl\u00e7is\u00eb s\u00eb dhjamosur, e njohur si MASLD, lidhet me mbipesh\u00ebn, rezistenc\u00ebn ndaj insulin\u00ebs dhe diabetin e tipit 2. 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